Brook Byers

Founder

Brook Byers has been a venture capital investor since 1972. He has been closely involved with founders to help build more than 60 new technology-based companies. He formed the first life sciences practice group in the venture capital profession in 1984 and led Kleiner Perkins to become a premier venture capital firm in the life sciences, healthcare and biotechnology sectors.

  

Brook was the founding president and then chairman of four biotechnology companies that were incubated in Kleiner Perkins' offices and went on to become public companies with an aggregate market value of more than US$8 billion. He currently serves on the board of directors of Arsenal Bio, Octave Bio, Newsela and Verana Health. Brook serves on the board of the Stanford Center for BioDesign and is a Lifetime Board Member of the University of California San Francisco Medical Center. He served on the Board of Trustees of Stanford University, the Asian Art Museum in San Francisco and the Georgia Tech Advisory Board. He was also a founder of TechNet.

  

Raised in Atlanta, Georgia, Brook graduated with a bachelor’s degree in electrical engineering from Georgia Tech and received an M.B.A. from Stanford University. He received an Honorary PhD from Georgia Tech.

Nonprofit Boards

— UCSF Foundation Board – Lifetime Director

— UCSF Innovation and Partnerships Board

— Stanford Medicine Advisory Board

— Stanford BioDesign Advisory Board

— New Schools Venture Fund Board

Brook Byers
Companies Backed
Disruptive cell-based therapies
Disruptive cell-based therapies
Alumni (Acquired by Gilead Sciences)
Molecular diagnostics
Molecular diagnostics
Alumni (Myriad Genetics)
Inspiring the world through play
Inspiring the world through play
Alumni
Driving advancement in cancer genomics
Driving advancement in cancer genomics
Alumni (Acquired by Roche)
Delivering on the promise of biotechnology
Delivering on the promise of biotechnology
Alumni (Acquired by Roche)
Genetic research and cancer detection
Genetic research and cancer detection
Alumni (Acquired by Exact Sciences)
Addressing unmet clinical need in ophthamology
Addressing unmet clinical need in ophthamology
Alumni (Acquired by Allergan)
Life-improving vision technologies
Life-improving vision technologies
Alumni (Acquired by Abbott)
Q&A
  • How did you get interested in science?

    As a youngster growing up in Georgia, I was a tinkerer, a habit my parents indulged with ham-radio kits and chemistry sets. I had a high school teacher who took me under his wing; he gave me extra science homework and took me to visit the labs at Georgia Tech, which is where I ended up going to college to study electrical engineering and physics.

  • You joined Kleiner Perkins in the early days. How did you end up here?

    I saw venture capital as an opportunity to capitalize on my lifelong passion for science, to work with scientists and engineers to create new products and build companies. Early on, I apprenticed with Pitch Johnson, the venture capital pioneer. In 1977, Eugene Kleiner and Tom Perkins invited me to join them as they expanded Kleiner Perkins. Pitch supported my move; we collaborated on several investments. At the time, venture capital was like that—people worked together and helped each other. It’s still the way I like to work.

  • You’ve focused on life-sciences companies. How did that come about?

    Kleiner had incubated Genentech, which pioneered the use of recombinant DNA technology to develop drugs for the most serious diseases. I’ve been interested in biotech ever since. I am particularly proud of Rituxan, a monoclonal antibody therapy discovered at a company I incubated at Kleiner Perkins, serving as the company’s first CEO. Over 4.4 million patients have been treated for cancer and autoimmune diseases with Rituxan.

  • What do you look for in entrepreneurs?

    It’s a tough and sometimes lonely job being a founder; it takes a special people person to succeed. They must be bold, ambitious, collaborative and a natural leader.

  • How do you view your role when you invest in a young company?

    My role with founders is to serve as mentor/coach, applying my experience to help them manage the ups and downs of the entrepreneurial journey. Like all good relationships, it requires shared passion, honesty, courage—and, every so often, humility and candor.

  • Outside of venture, what interests you?

    Anyone who walks into my office knows two things about me immediately: I collect art, and I like music. Both have brought rich dimension to my life and kept things in perspective. As the Grateful Dead sang: “Sometimes the lights are shining on me…sometimes I can barely see….lately it occurs to me….what a long, strange trip it’s been.”

Perspectives